SCHEMBL2867366

SCHEMBL2867366

Clc1ccc(-c2c[nH]c(Cc3ccccc3)n2)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 1/20 0.48
NR1H2 P55055 3/20 0.43
ALOX5 P09917 1/20 0.41
PSD A5PKW4 2/20 0.41
GSK3B P49841 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NR1H3 Q13133 2/20 0.40
KMO O15229 3/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
NPY5R Q15761 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
POLB P06746 2/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31305571 1.00 CXCR2 (0.48) CXCR2NR1H2ALOX5PSDGSK3B
SCHEMBL26113975 0.88 GSK3B (0.41) CXCR2NR1H2GSK3BTSHRTDP1
SCHEMBL31305556 0.88 NR1H2 (0.40) CXCR2NR1H2KMO
SCHEMBL2871695 0.88 NR1H2 (0.40) CXCR2NR1H2KMO
SCHEMBL5755658 0.88 ADORA2A (0.44) CXCR2KMO
SCHEMBL31305393 0.88 ADORA2A (0.44) CXCR2KMO
SCHEMBL2868741 0.87 CXCR2 (0.40) CXCR2GSK3BMAPK1SMN1; SMN2POLB
SCHEMBL31305579 0.87 CXCR2 (0.40) CXCR2GSK3BMAPK1SMN1; SMN2POLB
SCHEMBL31305503 0.87 ADORA2A (0.44) CXCR2GSK3BTSHRMAPK1TDP1
SCHEMBL28403330 0.87 CYP3A4 (0.40) CXCR2GSK3BKMONPY5RKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215572-A1 SURFACE TREATMENT AGENT FOR COPPER OR COPPER ALLOY SHIKOKU CHEMICALS CORPORATION (JP) 2025-07-03 US disclosed
EP-4506488-A1 SURFACE TREATMENT AGENT FOR COPPER OR COPPER ALLOY Shikoku Chemicals Corporation (JP) 2025-02-12 EP disclosed
WO-2023190263-A1 SURFACE TREATMENT AGENT FOR COPPER OR COPPER ALLOY 四国化成工業株式会社 2023-10-05 WO disclosed
WO-2010016620-A1 SURFACE TREATING AGENT FOR COPPER OR COPPER ALLOY AND USE THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2010-02-11 WO disclosed