Toluene

Toluene

SCHEMBL28675004

CC(O)=S.CCOC(=O)CCC(O)=S.Cc1ccccc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.51
CYP4F2 P78329 3/20 0.46
CYP4A11 Q02928 3/20 0.46
TSHR P16473 1/20 0.43
TOP2A P11388 2/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALOX5 P09917 1/20 0.42
NOTUM Q6P988 1/20 0.42
PTPN1 P18031 1/20 0.41
CREBBP Q92793 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21633321 0.86 CYP1A2 (0.47) SMN1; SMN2CYP4F2CYP4A11TSHRALDH1A1
Toluene SCHEMBL28111602 0.85 SMN1; SMN2 (0.55) SMN1; SMN2CYP4F2CYP4A11TSHRTOP2A
Toluene SCHEMBL242077 0.83 SMN1; SMN2 (0.57) SMN1; SMN2CYP4F2CYP4A11TSHRTOP2A
Toluene SCHEMBL8513838 0.81 SMN1; SMN2 (0.54) SMN1; SMN2CYP4F2CYP4A11TSHRTOP2A
Toluene SCHEMBL28096369 0.81 CYP4F2 (0.61) SMN1; SMN2CYP4F2CYP4A11TOP2AALDH1A1
Toluene SCHEMBL27384298 0.80 SMN1; SMN2 (0.54) SMN1; SMN2CYP4F2CYP4A11TSHRTOP2A
Toluene SCHEMBL11727486 0.80 CYP4F2 (0.56) SMN1; SMN2CYP4F2CYP4A11TSHRTOP2A
Toluene SCHEMBL573822 0.80 CYP4F2 (0.56) SMN1; SMN2CYP4F2CYP4A11TSHRTOP2A
Toluene SCHEMBL27711158 0.80 CYP1A2 (0.55) SMN1; SMN2CYP4F2CYP4A11TSHRTOP2A
Ethyl Propionate SCHEMBL27658259 0.77 MEN1 (0.52) SMN1; SMN2CYP4F2CYP4A11TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113474376-A Rubber latex and aqueous adhesive composition 电化株式会社 2021-10-01 CN disclosed