Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950607 | 0.88 | HDAC6 (0.68) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL21224494 | 0.87 | HDAC6 (0.67) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL21224492 | 0.87 | HDAC6 (0.67) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL31173179 | 0.87 | HDAC6 (0.54) | HDAC6HDAC4GAAMRE11 | |
| SCHEMBL21224198 | 0.86 | HDAC6 (0.66) | HDAC6HDAC1MAPTALDH1A1ELOVL1 | |
| SCHEMBL21224196 | 0.86 | HDAC6 (0.66) | HDAC6HDAC1MAPTALDH1A1ELOVL1 | |
| SCHEMBL21224178 | 0.85 | HDAC6 (0.70) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL21224180 | 0.85 | HDAC6 (0.70) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL22971724 | 0.84 | HDAC6 (0.63) | HDAC6MAPTALDH1A1ELOVL1GAA | |
| SCHEMBL21241836 | 0.84 | HDAC6 (0.63) | HDAC6MAPTALDH1A1ELOVL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113645971-B | Compounds and uses thereof | 福宏治疗公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-113645971-A | Compound and use thereof | 福宏治疗公司 | 2021-11-12 | — | — | CN | disclosed |