Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | GLA | P06280 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792513 | 1.00 | KDM4E (0.67) | KDM4EALDH1A1GLAGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11265359 | 0.98 | KDM4E (0.65) | KDM4EALDH1A1GLAGAASMN1; SMN2 | |
| SCHEMBL11549158 | 0.84 | KDM4E (0.74) | KDM4EALDH1A1GLAGAASMN1; SMN2 | |
| SCHEMBL8969938 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1GLAGAASMN1; SMN2 | |
| SCHEMBL28659594 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1GLAGAASMN1; SMN2 | |
| SCHEMBL13256676 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1GLAGAASMN1; SMN2 | |
| SCHEMBL28355634 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1GLAGAASMN1; SMN2 | |
| SCHEMBL28381549 | 0.81 | ALPG (0.48) | KDM4EALDH1A1GLAGAASMN1; SMN2 | |
| SCHEMBL2427657 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1GLAGAASMN1; SMN2 | |
| SCHEMBL11569234 | 0.80 | KDM4E (0.68) | KDM4EALDH1A1GLAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659004-A | Phenothiazine polymerization inhibitor containing pyridoquinazolinone, and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117659004-A | Phenothiazine polymerization inhibitor containing pyridoquinazolinone, and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110252351-B | Application of copper catalyst in catalyzing reaction of 1-pyridyl indole compound and tert-butyl nitrite | 苏州大学 | 2021-12-10 | — | — | CN | disclosed |