Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29907567 | 1.00 | KRAS (0.47) | KRAS | |
| SCHEMBL29828462 | 1.00 | KRAS (0.47) | KRAS | |
| SCHEMBL29907565 | 0.96 | KRAS (0.46) | KRAS | |
| SCHEMBL30767905 | 0.96 | KRAS (0.46) | KRAS | |
| SCHEMBL29828329 | 0.96 | KRAS (0.46) | KRAS | |
| SCHEMBL29907423 | 0.96 | KRAS (0.46) | KRAS | |
| SCHEMBL29163255 | 0.96 | KRAS (0.46) | KRAS | |
| SCHEMBL28676689 | 0.96 | KRAS (0.46) | KRAS | |
| SCHEMBL27145217 | 0.93 | KRAS (0.49) | KRAS | |
| SCHEMBL31220148 | 0.92 | KRAS (0.48) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117645614-A | Substituted heterocyclo-cyclic compounds, preparation and pharmaceutical use thereof | 劲方医药科技(上海)有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-115057872-A | Substituted heterocyclic ring compound, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-113853373-B | Substituted heterocyclic ring compound, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-113853373-A | Substituted heterocyclic ring compound, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2021-12-28 | — | — | CN | disclosed |