Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 17/20 | 0.68 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30483793 | 0.92 | KRAS (0.80) | KRAS | |
| SCHEMBL24558337 | 0.92 | KRAS (0.80) | KRAS | |
| SCHEMBL29693152 | 0.90 | KRAS (0.65) | KRASHTR2AHTR2CHTR2B | |
| SCHEMBL24558249 | 0.90 | KRAS (0.65) | KRASHTR2AHTR2CHTR2B | |
| SCHEMBL28654630 | 0.85 | KRAS (0.84) | KRAS | |
| SCHEMBL28650748 | 0.85 | KRAS (0.63) | KRAS | |
| SCHEMBL26883204 | 0.84 | KRAS (0.55) | KRASHTR2AHTR2CHTR2BTSHR | |
| SCHEMBL31107225 | 0.84 | KRAS (0.55) | KRASHTR2AHTR2CHTR2BTSHR | |
| SCHEMBL28669292 | 0.84 | KRAS (0.82) | KRAS | |
| SCHEMBL28671358 | 0.84 | KRAS (0.63) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113508118-A | Fused tricyclic compounds useful as anticancer agents | 阿斯利康(瑞典)有限公司 | 2021-10-15 | — | — | CN | disclosed |