Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 17/20 | 0.58 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658817 | 0.92 | KRAS (0.66) | KRASMGLL | |
| SCHEMBL28659228 | 0.90 | KRAS (0.56) | KRASMGLL | |
| SCHEMBL24558262 | 0.90 | KRAS (0.54) | KRAS | |
| SCHEMBL29693086 | 0.90 | KRAS (0.54) | KRAS | |
| SCHEMBL28658799 | 0.89 | KRAS (0.55) | KRASKCNJ1 | |
| SCHEMBL28668876 | 0.88 | KRAS (0.55) | KRASMGLL | |
| SCHEMBL28670544 | 0.88 | KRAS (0.61) | KRASMGLL | |
| SCHEMBL31107247 | 0.82 | KRAS (0.61) | KRAS | |
| SCHEMBL24558440 | 0.82 | KRAS (0.61) | KRAS | |
| SCHEMBL28655430 | 0.81 | KRAS (0.56) | KRASMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113508118-A | Fused tricyclic compounds useful as anticancer agents | 阿斯利康(瑞典)有限公司 | 2021-10-15 | — | — | CN | disclosed |