Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16263321 | 0.78 | HPGD (0.47) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL1848025 | 0.78 | HPGD (0.47) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL879540 | 0.77 | HPGD (0.50) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL879545 | 0.77 | HPGD (0.50) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL4718747 | 0.77 | HPGD (0.46) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL8736286 | 0.76 | HPGD (0.45) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL3415092 | 0.75 | HPGD (0.49) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL8736324 | 0.74 | HPGD (0.47) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| Butane SCHEMBL28323353 | 0.74 | HPGD (0.60) | HPGDSMN1; SMN2USP2MEN1KMT2A | |
| SCHEMBL20221455 | 0.74 | HPGD (0.44) | HPGDSMN1; SMN2USP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-B | Substituted pyrazolo [1,5-A ] pyridine compounds as RET kinase inhibitors | 阿雷生物药品公司 | 2021-12-14 | — | — | CN | disclosed |