Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | LOX | P28300 | 1/20 | 0.71 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.71 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.71 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL909963 | 1.00 | — | — | |
| Oxalic Acid SCHEMBL11876639 | 0.92 | KMT2A (0.70) | KMT2AMEN1LOXLOXL3LOXL2 | |
| Carbamic Acid SCHEMBL28684032 | 0.92 | — | — | |
| Fumaric Acid SCHEMBL694 | 0.85 | MEN1 (1.00) | KMT2AMEN1LOXLOXL3LOXL2 | |
| Propionic Acid SCHEMBL28712838 | 0.85 | KMT2A (0.61) | KMT2AMEN1LOXLOXL3LOXL2 | |
| Beta-Alanine SCHEMBL28248711 | 0.85 | KMT2A (0.61) | KMT2AMEN1LOXLOXL3LOXL2 | |
| Fumaric Acid SCHEMBL28115011 | 0.85 | MEN1 (1.00) | KMT2AMEN1LOXLOXL3LOXL2 | |
| Fumaric Acid SCHEMBL695 | 0.85 | MEN1 (1.00) | KMT2AMEN1LOXLOXL3LOXL2 | |
| SCHEMBL339 | 0.84 | — | — | |
| SCHEMBL27565622 | 0.84 | LOX (1.00) | KMT2AMEN1LOXLOXL3LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311184-B | Prepreg, fiber-reinforced composite material, and surface-modified reinforcing fiber | 帝人株式会社 | 2022-01-18 | — | — | CN | disclosed |