SCHEMBL2867928

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4327002	0.85	HPGD (0.58)	HPGDMAPK1POLBNPC1MEN1
	SCHEMBL4328143	0.85	HPGD (0.53)	HPGDMAPK1POLBNPC1MEN1
	SCHEMBL4340981	0.85	HPGD (0.52)	HPGDMAPK1POLBNPC1MEN1
	SCHEMBL4336101	0.85	HPGD (0.57)	HPGDMAPK1POLBNPC1MEN1
	SCHEMBL13927641	0.83	HPGD (0.52)	HPGDMAPK1POLBNPC1MEN1
	SCHEMBL4334956	0.82	HPGD (0.53)	HPGDPOLBNPC1MEN1PKM
	SCHEMBL4329145	0.82	HPGD (0.48)	HPGDPOLBNPC1MEN1KMT2A
	SCHEMBL4339183	0.79	HPGD (0.48)	HPGDMAPK1POLBNPC1MEN1
	SCHEMBL2862134	0.79	CSNK1D (0.54)	MAPK1TTKMAPK3CSNK1D
	SCHEMBL2870086	0.78	KDM4E (0.54)	HPGDMAPK1TTKMAPK3CSNK1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.