Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865042 | 0.80 | — | — | |
| SCHEMBL10929135 | 0.78 | — | — | |
| SCHEMBL9244038 | 0.74 | TSHR (0.52) | TSHRKMT2AMEN1SLC1A1HSD17B10 | |
| SCHEMBL7784845 | 0.72 | TSHR (0.50) | TSHRKMT2AMEN1SLC1A1HSD17B10 | |
| SCHEMBL8399384 | 0.72 | TSHR (0.50) | TSHRKMT2AMEN1SLC1A1HSD17B10 | |
| SCHEMBL16329096 | 0.72 | TSHR (0.50) | TSHRKMT2AMEN1SLC1A1HSD17B10 | |
| SCHEMBL11544587 | 0.71 | TSHR (0.48) | TSHRKMT2AMEN1SLC1A1HSD17B10 | |
| SCHEMBL14354976 | 0.71 | SLC1A1 (0.49) | TSHRKMT2AMEN1SLC1A1HSD17B10 | |
| SCHEMBL5313852 | 0.70 | — | — | |
| SCHEMBL125808 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113577299-A | ROS-responsive monoclonal antibody drug oral nanoparticle and preparation method thereof | 浙江大学医学院附属第一医院 | 2021-11-02 | — | — | CN | claimed |
| CN-113577299-A | ROS-responsive monoclonal antibody drug oral nanoparticle and preparation method thereof | 浙江大学医学院附属第一医院 | 2021-11-02 | — | — | CN | disclosed |