SCHEMBL28680544

SCHEMBL28680544

Cc1ccc(OP(=O)(O)OOC(=O)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.47
F2 P00734 1/20 0.47
TSHR P16473 4/20 0.46
ALDH1A1 P00352 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CYP3A4 P08684 1/20 0.44
PTK2B Q14289 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
MAPT P10636 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 2/20 0.41
SRC P12931 1/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28678889 0.92 CYP3A4 (0.48) LMNATSHRALDH1A1TDP1CYP3A4
SCHEMBL28674015 0.88 TSHR (0.53) LMNAF2TSHRALDH1A1HSD17B10
SCHEMBL28680542 0.86 TSHR (0.46) LMNATSHRTDP1CYP3A4PTK2B
SCHEMBL28687011 0.86 HPGD (0.43) LMNAF2TSHRALDH1A1HSD17B10
SCHEMBL28672554 0.84 CYP2C19 (0.51) LMNATSHRALDH1A1TDP1CYP3A4
SCHEMBL28681226 0.83 MAPT (0.47) LMNATSHRALDH1A1HSD17B10TDP1
SCHEMBL28931874 0.83 PRSS1 (0.41) TSHRALDH1A1TDP1CYP3A4NPC1
SCHEMBL28697487 0.83 PRSS1 (0.41) TSHRALDH1A1TDP1CYP3A4NPC1
SCHEMBL28676538 0.82 CYP3A4 (0.49) LMNAF2TSHRALDH1A1TDP1
SCHEMBL218003 0.80 CYP3A4 (0.57) LMNATSHRALDH1A1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN claimed
CN-113929797-A Solid catalyst component and catalyst system for producing polymers 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-113929798-A Solid catalyst component and catalyst system for olefin polymerization 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-113929799-A Catalyst component for olefin polymerization, catalyst system and application 中国石油化工股份有限公司 2022-01-14 CN claimed