SCHEMBL28680598

SCHEMBL28680598

CC=CCCc1cn(C)c2ccccc12

nearest known ligand 0.66

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.66
GPR84 Q9NQS5 1/20 0.59
KEAP1 Q14145 1/20 0.52
NFE2L2 Q16236 1/20 0.52
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
KDM4E B2RXH2 2/20 0.49
HSD17B10 Q99714 2/20 0.49
HPGD P15428 1/20 0.49
SLC6A4 P31645 1/20 0.48
TP53 P04637 2/20 0.47
CA2 P00918 1/20 0.46
RXFP1 Q9HBX9 2/20 0.44
LMNA P02545 2/20 0.44
ALDH1A1 P00352 2/20 0.44
IMPDH2 P12268 1/20 0.44
GLA P06280 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
AHR P35869 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21912937 0.83 HTR2A (0.65) HTR2AGPR84KEAP1NFE2L2KMT2A
SCHEMBL6943161 0.82 HTR2A (0.63) HTR2AGPR84KEAP1NFE2L2KMT2A
SCHEMBL32679648 0.82 HTR2A (0.63) HTR2AGPR84KEAP1NFE2L2KMT2A
SCHEMBL6939255 0.82 HTR2A (0.63) HTR2AGPR84KEAP1NFE2L2KMT2A
SCHEMBL332959 0.80 HTR2A (1.00) HTR2AGPR84KEAP1NFE2L2KDM4E
SCHEMBL7004405 0.79 HTR2A (0.73) HTR2AGPR84KEAP1NFE2L2KMT2A
SCHEMBL9889542 0.78 HTR2A (0.71) HTR2AGPR84KEAP1NFE2L2KMT2A
Water SCHEMBL27796071 0.77 HTR2A (0.93) HTR2AGPR84KEAP1NFE2L2KDM4E
SCHEMBL28930586 0.76 HTR2A (0.59) HTR2AGPR84KEAP1NFE2L2KMT2A
SCHEMBL15453266 0.76 HTR2A (0.59) HTR2AGPR84KEAP1NFE2L2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113880871-B Preparation method of saturated monoboron compound 中国科学院兰州化学物理研究所 2022-08-23 CN disclosed
CN-113880871-A Preparation method of saturated monoboron compound 中国科学院兰州化学物理研究所 2022-01-04 CN disclosed