Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.91 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.91 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.63 |
| ▸ | HTR1D | P28221 | 8/20 | 0.60 |
| ▸ | HTR1A | P08908 | 7/20 | 0.60 |
| ▸ | HTR1B | P28222 | 5/20 | 0.60 |
| ▸ | HTR2C | P28335 | 4/20 | 0.60 |
| ▸ | HTR7 | P34969 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | HTR6 | P50406 | 3/20 | 0.60 |
| ▸ | HTR2B | P41595 | 2/20 | 0.60 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.60 |
| ▸ | HTR5A | P47898 | 2/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.60 |
| ▸ | HTR3B | O95264 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724496 | 0.95 | HTR2A (1.00) | HTR2ATRPM8GPR84HTR1DHTR1A | |
| SCHEMBL626030 | 0.95 | HTR2A (1.00) | HTR2ATRPM8GPR84HTR1DHTR1A | |
| Methane SCHEMBL26617454 | 0.94 | HTR2A (0.97) | HTR2ATRPM8GPR84HTR1DHTR1A | |
| Hydrochloric Acid SCHEMBL892839 | 0.94 | HTR2A (0.97) | HTR2ATRPM8GPR84HTR1DHTR1A | |
| Hydrochloric Acid SCHEMBL686594 | 0.94 | HTR2A (0.97) | HTR2ATRPM8GPR84HTR1DHTR1A | |
| Oxalic Acid SCHEMBL27132838 | 0.87 | HTR2A (0.83) | HTR2ATRPM8GPR84HTR1DHTR1A | |
| Oxalic Acid SCHEMBL30724502 | 0.87 | HTR2A (0.83) | HTR2ATRPM8GPR84HTR1DHTR1A | |
| SCHEMBL892989 | 0.86 | HTR2A (0.82) | HTR2ATRPM8GPR84HTR1DHTR1A | |
| Oxalic Acid SCHEMBL27125982 | 0.85 | HTR2A (0.81) | HTR2ATRPM8GPR84HTR1DHTR1A | |
| Oxalic Acid SCHEMBL30724503 | 0.85 | HTR2A (0.81) | HTR2ATRPM8GPR84HTR1DHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775284-A | Five-membered double-spiro indoline derivative and preparation method and application thereof | 中苏圆科技集团有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-117924298-B | Spiro indolone derivative diastereomer and preparation method and application thereof | 苏州大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-119775284-A | Five-membered double-spiro indoline derivative and preparation method and application thereof | 中苏圆科技集团有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-118878546-B | Spirobutyric acid derivative and preparation method and application thereof | 苏州大学 | 2025-01-03 | — | — | CN | disclosed |
| CN-118878546-A | Spirobutyric acid derivative and preparation method and application thereof | 苏州大学 | 2024-11-01 | — | — | CN | disclosed |
| CN-117924298-A | Spiro indolone derivative diastereomer and preparation method and application thereof | 苏州大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-113845523-B | Polycyclic quinoline derivatives, their preparation and use | 苏州大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-113845523-A | Polycyclic quinoline derivatives, their preparation and use | 苏州大学 | 2021-12-28 | — | — | CN | disclosed |