SCHEMBL28684268

SCHEMBL28684268

C/C(C#N)=C1/CCN(C(=O)O)C1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BPTF Q12830 1/20 0.33
NOTUM Q6P988 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28684250 1.00 BPTF (0.33) BPTFNOTUMMEN1KMT2A
SCHEMBL15939328 0.89 BPTF (0.32) BPTFNOTUMMEN1KMT2A
SCHEMBL28682513 0.78 ESR2 (0.46) MEN1KMT2A
SCHEMBL28682642 0.78 ESR2 (0.46) MEN1KMT2A
SCHEMBL29360309 0.74 SMN1; SMN2 (0.46) MEN1KMT2A
SCHEMBL20995023 0.72 MEN1 (0.57) MEN1KMT2A
SCHEMBL22468561 0.71 DPP8 (0.33) NOTUM
SCHEMBL28673825 0.71 DPP8 (0.33) NOTUM
SCHEMBL22468423 0.71 DPP8 (0.33) NOTUM
SCHEMBL3134009 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113874381-A Inhibitors of RAF kinase 金耐特生物制药公司 2021-12-31 CN disclosed