Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2231418 | 0.90 | MEN1 (0.63) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL29365686 | 0.90 | MEN1 (0.63) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL105865 | 0.90 | MEN1 (0.63) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL28135141 | 0.90 | MEN1 (0.63) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL30288909 | 0.90 | MEN1 (0.63) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL283196 | 0.86 | MEN1 (0.59) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL29506706 | 0.86 | MEN1 (0.59) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL22618115 | 0.86 | MEN1 (0.59) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL5494116 | 0.85 | MEN1 (0.57) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL17816646 | 0.85 | MEN1 (0.57) | MEN1KMT2AKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979903-B | Organic thermal activation delayed fluorescence material containing phenylsulfone-spirofluorene structural unit, preparation method and application | 杭州师范大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-113979903-A | Organic thermal activation delayed fluorescent material containing phenylsulfone-spirofluorene structural unit, preparation method and application | 杭州师范大学 | 2022-01-28 | — | — | CN | disclosed |