Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MYOC | Q99972 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688348 | 1.00 | AR (0.52) | ARMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL28688534 | 0.89 | AR (0.65) | ARMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL28688535 | 0.89 | AR (0.65) | ARMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL28664095 | 0.87 | AR (0.54) | AR | |
| SCHEMBL28664094 | 0.87 | AR (0.54) | AR | |
| SCHEMBL28660355 | 0.77 | AR (0.70) | AR | |
| SCHEMBL28485733 | 0.76 | AR (0.69) | AR | |
| SCHEMBL28660373 | 0.76 | AR (0.69) | AR | |
| SCHEMBL22565172 | 0.76 | AR (0.69) | AR | |
| SCHEMBL28688341 | 0.76 | AR (0.54) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735845-A | Androgen receptor degradation agent and application thereof | 梅德盛 | 2021-12-03 | — | — | CN | disclosed |