Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022164 | 0.82 | HDAC4 (0.33) | HDAC4APPPDK2 | |
| SCHEMBL11041122 | 0.76 | HSD17B10 (0.30) | HDAC4 | |
| SCHEMBL17868279 | 0.72 | MYC (0.32) | — | |
| SCHEMBL5619157 | 0.69 | MEN1 (0.34) | — | |
| SCHEMBL4995457 | 0.67 | CYP3A4 (0.38) | — | |
| SCHEMBL28483994 | 0.67 | APP (0.30) | HDAC4APP | |
| SCHEMBL30173231 | 0.64 | — | — | |
| SCHEMBL4227473 | 0.64 | — | — | |
| SCHEMBL28370555 | 0.64 | — | — | |
| SCHEMBL17802618 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113853372-A | Thio-heterocyclic exchange chemistry and uses thereof | 弗吉尼亚大学专利基金委员会 | 2021-12-28 | — | — | CN | disclosed |