Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.68 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.67 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28675155 | 0.93 | HDAC6 (0.66) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28678678 | 0.93 | HDAC6 (0.73) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28666328 | 0.90 | HDAC6 (0.80) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28672522 | 0.88 | HDAC6 (0.63) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28667046 | 0.87 | HDAC6 (0.67) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28680230 | 0.87 | HDAC6 (0.70) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28661805 | 0.87 | HDAC6 (0.73) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28667049 | 0.86 | HDAC6 (0.67) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28665589 | 0.85 | HDAC6 (0.70) | HDAC6HDAC1HDAC10HDAC8HDAC3 | |
| SCHEMBL28689645 | 0.84 | PTGDR2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113845522-B | Aminopeptidase N inhibitor and preparation method and application thereof | 山东省药学科学院 | 2024-05-14 | — | — | CN | claimed |
| CN-113845522-A | Aminopeptidase N inhibitor and preparation method and application thereof | 山东省药学科学院 | 2021-12-28 | — | — | CN | claimed |
| CN-113845522-B | Aminopeptidase N inhibitor and preparation method and application thereof | 山东省药学科学院 | 2024-05-14 | — | — | CN | disclosed |
| CN-113845522-A | Aminopeptidase N inhibitor and preparation method and application thereof | 山东省药学科学院 | 2021-12-28 | — | — | CN | disclosed |