SCHEMBL28689663

SCHEMBL28689663

Cc1ccccc1OP(=O)(O)OOC(=O)C(C)C

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.37
KDM4E B2RXH2 3/20 0.37
TDP1 Q9NUW8 3/20 0.37
NOTUM Q6P988 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HPGD P15428 2/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
USP2 O75604 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PDE3A Q14432 1/20 0.34
HSD17B10 Q99714 1/20 0.34
LMNA P02545 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30367321 0.87 KDM4E (0.38) MAPTKDM4ETDP1NOTUMNPSR1
SCHEMBL28673147 0.83 MAPT (0.40) MAPTKDM4ETDP1NOTUMNPSR1
SCHEMBL28695423 0.82 TDP1 (0.39) MAPTKDM4ETDP1NOTUMNPSR1
SCHEMBL28680419 0.79 F2 (0.46) MAPTKDM4ETDP1NOTUMHPGD
SCHEMBL28678897 0.79 MAPT (0.39) MAPTKDM4ETDP1NOTUMNPSR1
SCHEMBL497602 0.79 KDM4E (0.47) MAPTKDM4ENOTUMNPSR1HPGD
SCHEMBL28698447 0.79 HPGD (0.40) MAPTTDP1NPSR1HPGDMEN1
SCHEMBL28696137 0.78 TDP1 (0.43) MAPTTDP1NPSR1MEN1KMT2A
Fluoride SCHEMBL31047191 0.77 KDM4E (0.46) MAPTKDM4ENOTUMNPSR1HPGD
SCHEMBL28680426 0.77 TSHR (0.47) NPSR1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN claimed
CN-113929797-A Solid catalyst component and catalyst system for producing polymers 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-113929799-A Catalyst component for olefin polymerization, catalyst system and application 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-113929798-A Solid catalyst component and catalyst system for olefin polymerization 中国石油化工股份有限公司 2022-01-14 CN claimed
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN disclosed
CN-113929797-A Solid catalyst component and catalyst system for producing polymers 中国石油化工股份有限公司 2022-01-14 CN disclosed
CN-113929799-A Catalyst component for olefin polymerization, catalyst system and application 中国石油化工股份有限公司 2022-01-14 CN disclosed
CN-113929798-A Solid catalyst component and catalyst system for olefin polymerization 中国石油化工股份有限公司 2022-01-14 CN disclosed