Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GUSB | P08236 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30263098 | 1.00 | MAPT (0.62) | MAPTMCL1NPC1KMT2ARAB9A | |
| SCHEMBL28689792 | 1.00 | MAPT (0.62) | MAPTMCL1NPC1KMT2ARAB9A | |
| SCHEMBL28692082 | 0.91 | MAPT (0.65) | MAPTMCL1NPC1KMT2ARAB9A | |
| SCHEMBL28692085 | 0.91 | MAPT (0.65) | MAPTMCL1NPC1KMT2ARAB9A | |
| SCHEMBL30263058 | 0.91 | MAPT (0.65) | MAPTMCL1NPC1KMT2ARAB9A | |
| SCHEMBL28669675 | 0.91 | MAPT (0.64) | MAPTMCL1NPC1KMT2ARAB9A | |
| SCHEMBL30263062 | 0.91 | MAPT (0.64) | MAPTMCL1NPC1KMT2ARAB9A | |
| SCHEMBL28669672 | 0.91 | MAPT (0.64) | MAPTMCL1NPC1KMT2ARAB9A | |
| SCHEMBL28661806 | 0.90 | MAPT (0.64) | MAPTMCL1NPC1KMT2ARAB9A | |
| SCHEMBL28661811 | 0.90 | MAPT (0.64) | MAPTMCL1NPC1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113735769-A | Quinolinone alkaloid derivative containing acylhydrazone structure at 3-position and preparation method and application thereof | 太原理工大学 | 2021-12-03 | — | — | CN | disclosed |