Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346832 | 0.89 | MAPT (0.49) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL29447084 | 0.89 | MAPT (0.49) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL1511509 | 0.84 | MAPT (0.49) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL9396485 | 0.79 | MAPT (0.52) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL28664013 | 0.77 | MAPT (0.51) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL11692881 | 0.76 | MAPT (0.48) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL5163517 | 0.76 | MAPT (0.64) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL6437317 | 0.76 | NPSR1 (0.52) | MAPTKMT2APOLBALDH1A1LMNA | |
| SCHEMBL7653533 | 0.76 | MAPT (0.55) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL22323978 | 0.76 | MAPT (0.53) | MAPTKMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114126613-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2022-03-01 | — | — | CN | disclosed |