Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.56 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | STAT3 | P40763 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TACR3 | P29371 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28681436 | 0.92 | STAT3 (0.61) | ALDH1A1CACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL28699068 | 0.91 | STAT3 (0.54) | ALDH1A1CACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL28699093 | 0.88 | CTDSP1 (0.62) | ALDH1A1CACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL28931754 | 0.88 | MEN1 (0.59) | ALDH1A1CACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL28696288 | 0.87 | CACNA1B (0.53) | ALDH1A1CACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL28693080 | 0.87 | STAT3 (0.64) | ALDH1A1CACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL28695985 | 0.87 | STAT3 (0.55) | ALDH1A1CACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL28697036 | 0.87 | MAPT (0.55) | ALDH1A1CACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL28683191 | 0.86 | MEN1 (0.54) | ALDH1A1CACNA1BAPBA1MEN1KMT2A | |
| SCHEMBL28673399 | 0.86 | MEN1 (0.58) | ALDH1A1CACNA1BAPBA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113747920-A | Immune checkpoint inhibitor combination therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-12-03 | — | — | CN | disclosed |
| CN-112703001-A | Combination cancer therapy using quinoline carboxamide derivatives | 株式会社益力多本社 | 2021-04-23 | — | — | CN | disclosed |