Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8154163 | 0.88 | FFAR1 (0.63) | NPC1RAB9AFFAR1CYP3A4HNF4A | |
| SCHEMBL8614274 | 0.86 | NPC1 (0.56) | NPC1RAB9AFFAR1KDM4EALDH1A1 | |
| SCHEMBL28684420 | 0.86 | FFAR1 (0.61) | NPC1RAB9AFFAR1KMT2ACAPN1 | |
| SCHEMBL2256468 | 0.84 | NPC1 (0.72) | NPC1RAB9AFFAR1KDM4EALDH1A1 | |
| SCHEMBL29479413 | 0.84 | NPC1 (0.72) | NPC1RAB9AFFAR1KDM4EALDH1A1 | |
| SCHEMBL27914957 | 0.83 | FFAR1 (0.58) | NPC1RAB9AFFAR1ALDH1A1MEN1 | |
| SCHEMBL29429098 | 0.82 | CA12 (0.54) | NPC1RAB9AFFAR1CA12CA2 | |
| SCHEMBL9198157 | 0.82 | FFAR1 (0.50) | NPC1RAB9AFFAR1CYP1A2CYP3A4 | |
| SCHEMBL28684394 | 0.82 | CA12 (0.54) | NPC1RAB9AFFAR1CA12CA2 | |
| SCHEMBL1550927 | 0.82 | FFAR1 (1.00) | FFAR1CHRM2S1PR1FPR1FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057623-B | N-naphthyl indole derivative and synthesis method thereof | 湖南第一师范学院 | 2023-07-21 | — | — | CN | disclosed |
| CN-114057623-A | N-naphthyl indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-18 | — | — | CN | disclosed |