SCHEMBL28692091

SCHEMBL28692091

CCCCCCCCCCCS.CCO[SiH](OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
THRB P10828 1/20 0.38
DNM1 Q05193 8/20 0.33
LSS P48449 1/20 0.31
ALDH1A1 P00352 3/20 0.31
LMNA P02545 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HSD17B10 Q99714 1/20 0.31
SLC22A1 O15245 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexanethiol SCHEMBL27492299 1.00 TSHR (0.38) TSHRTHRBDNM1LSSALDH1A1
SCHEMBL11788878 0.98 TSHR (0.33) TSHRTHRB
Tridecane SCHEMBL28187903 0.87 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
Decane SCHEMBL27897264 0.87 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL27659453 0.87 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
Nonane SCHEMBL29091995 0.87 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
Dodecane SCHEMBL6036923 0.87 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL27852473 0.87 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
Octane SCHEMBL22749440 0.87 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA
Octane SCHEMBL2389585 0.87 TSHR (0.50) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106033-A 3-alkyl propyl thioether-based triethoxysilane and preparation method and application thereof 山东阳谷华泰化工股份有限公司 2022-03-01 CN disclosed