Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28683476 | 0.90 | MEN1 (0.44) | NR1H2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21069366 | 0.86 | NR1H2 (0.49) | NR1H2NAMPTMEN1ALDH1A1MAPT | |
| SCHEMBL26092681 | 0.82 | NR1H2 (0.55) | NR1H2NAMPTMEN1ALDH1A1MAPT | |
| SCHEMBL15295766 | 0.82 | NR1H2 (0.51) | NR1H2NAMPTMEN1ALDH1A1MAPT | |
| SCHEMBL20572907 | 0.81 | NR1H2 (0.50) | NR1H2NAMPTMEN1ALDH1A1MAPT | |
| SCHEMBL23585483 | 0.79 | NR1H2 (0.54) | NR1H2NAMPTMEN1ALDH1A1MAPT | |
| SCHEMBL15295758 | 0.79 | NR1H2 (0.54) | NR1H2NAMPTMEN1ALDH1A1MAPT | |
| SCHEMBL17220371 | 0.79 | NR1H2 (0.48) | NR1H2NAMPTMEN1ALDH1A1MAPT | |
| SCHEMBL16399673 | 0.78 | HPGD (0.47) | HPGDRECQLGPR119KDM4EPKM | |
| SCHEMBL20233633 | 0.77 | NR1H2 (0.51) | NR1H2NAMPTMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943276-A | Nitrogen heterocyclic compound and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-01-18 | — | — | CN | disclosed |