Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 8/20 | 0.47 |
| ▸ | KDR | P35968 | 7/20 | 0.47 |
| ▸ | TEK | Q02763 | 7/20 | 0.47 |
| ▸ | BTK | Q06187 | 13/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | ITK | Q08881 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | BLK | P51451 | 2/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | TEC | P42680 | 1/20 | 0.43 |
| ▸ | TXK | P42681 | 1/20 | 0.43 |
| ▸ | BMX | P51813 | 1/20 | 0.43 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22659060 | 0.90 | BTK (0.53) | LCKKDRBTKEGFRITK | |
| SCHEMBL22676199 | 0.90 | BTK (0.53) | LCKKDRBTKEGFRITK | |
| SCHEMBL22673416 | 0.90 | BTK (0.53) | LCKKDRBTKEGFRITK | |
| SCHEMBL22659216 | 0.90 | SRC (0.53) | LCKKDRTEKBTKEGFR | |
| SCHEMBL22676631 | 0.87 | BTK (0.53) | LCKKDRBTKEGFRITK | |
| SCHEMBL22676069 | 0.82 | BTK (0.54) | LCKKDRBTKEGFRITK | |
| SCHEMBL30303790 | 0.82 | BTK (0.54) | LCKKDRBTKEGFRITK | |
| SCHEMBL22676705 | 0.82 | BTK (0.47) | LCKKDRTEKBTKFLT3 | |
| SCHEMBL22676702 | 0.82 | BTK (0.47) | LCKKDRTEKBTKFLT3 | |
| SCHEMBL30303364 | 0.82 | BTK (0.47) | LCKKDRTEKBTKFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114126620-A | FGFR inhibitors and methods of use thereof | 传达治疗有限公司 | 2022-03-01 | — | — | CN | disclosed |