SCHEMBL28694372

SCHEMBL28694372

CCOP(C)(=O)OCC=O

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 2/20 0.39
TP53 P04637 1/20 0.39
AOX1 Q06278 1/20 0.34
PPARD Q03181 2/20 0.33
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL281924 0.82
Phosphine SCHEMBL28536493 0.79 TSHR (0.65) TSHRTDP1TP53PPARDACHE
Fluoride SCHEMBL28031693 0.79 TSHR (0.56) TSHRTDP1TP53PPARDACHE
Water SCHEMBL28132240 0.79 TSHR (0.56) TSHRTDP1TP53PPARDACHE
SCHEMBL415775 0.79 TSHR (0.56) TSHRTDP1TP53PPARDACHE
SCHEMBL9648810 0.78 TSHR (0.65) TSHRTDP1TP53AOX1PPARD
SCHEMBL27863261 0.74 TSHR (0.40) TSHRTDP1TP53AOX1PPARD
SCHEMBL14332291 0.73 TSHR (0.39) TSHRTDP1TP53PPARD
SCHEMBL31520565 0.71 TDP1 (0.38) TSHRTDP1TP53PPARD
SCHEMBL575135 0.70 TSHR (0.46) TSHRTDP1TP53PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163471-A Preparation method of long-chain homoserine derivative 南京华狮新材料有限公司 2022-03-11 CN disclosed