SCHEMBL28696124

SCHEMBL28696124

C=C1N(C)c2cc(C(F)(F)F)ccc2C1(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KIF11 P52732 3/20 0.35
HSPA9 P38646 4/20 0.34
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
NOTUM Q6P988 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PKM P14618 1/20 0.33
OPRM1 P35372 2/20 0.32
OPRL1 P41146 1/20 0.32
MEN1 O00255 2/20 0.31
CYP1A2 P05177 2/20 0.31
TSHR P16473 2/20 0.31
KMT2A Q03164 2/20 0.31
HSP90AA1 P07900 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9750166 0.87 MPI (0.40) MPITDP1KIF11HSPA9NOTUM
SCHEMBL25562915 0.85 TDP1 (0.41) MPITDP1KIF11ALDH1A1PKM
SCHEMBL4602685 0.78 TDP1 (0.45) MPITDP1HTR2AHTR2CALDH1A1
SCHEMBL2185507 0.75 TDP1 (0.43) MPITDP1ALDH1A1MEN1KMT2A
SCHEMBL4602213 0.75 TDP1 (0.43) MPITDP1PKMOPRL1MEN1
SCHEMBL5464264 0.74 MPI (0.56) MPITDP1MEN1KMT2AMAPT
SCHEMBL11738860 0.72 TDP1 (0.41) MPITDP1KIF11ALDH1A1PKM
SCHEMBL12438154 0.72 MPI (0.41) MPITDP1
SCHEMBL4602650 0.72 TDP1 (0.41) MPITDP1HTR2AHTR2CALDH1A1
SCHEMBL13619868 0.71 MPI (0.40) MPITDP1HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113943493-A Method for synthesizing spirooxazine photochromic dye by using microchannel reactor 广州盛色科技有限公司 2022-01-18 CN disclosed