Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20944889 | 1.00 | PTPN11 (0.37) | PTPN11 | |
| SCHEMBL16925303 | 1.00 | PTPN11 (0.37) | PTPN11 | |
| SCHEMBL20944888 | 1.00 | PTPN11 (0.37) | PTPN11 | |
| SCHEMBL29715680 | 1.00 | PTPN11 (0.37) | PTPN11 | |
| SCHEMBL29308994 | 0.85 | PTPN11 (0.36) | PTPN11 | |
| SCHEMBL23022504 | 0.81 | PTPN11 (0.40) | PTPN11 | |
| SCHEMBL23022465 | 0.81 | PTPN11 (0.40) | PTPN11 | |
| SCHEMBL21287260 | 0.78 | — | — | |
| SCHEMBL21287146 | 0.78 | — | — | |
| SCHEMBL22799019 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311848-B | Novel heterocyclic derivatives useful as SHP2 inhibitors | 北京加科思新药研发有限公司 | 2022-02-01 | — | — | CN | disclosed |