Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylamide SCHEMBL10699905 | 0.80 | KDM4E (0.73) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| Salicylamide SCHEMBL27497234 | 0.77 | KDM4E (1.00) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| Salicylamide SCHEMBL21646 | 0.77 | KDM4E (1.00) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| Salicylamide SCHEMBL29384763 | 0.77 | KDM4E (1.00) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| Salicylamide SCHEMBL28153581 | 0.75 | KDM4E (0.86) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| Salicylamide SCHEMBL29288267 | 0.75 | KDM4E (0.86) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| Salicylamide SCHEMBL11412975 | 0.75 | KDM4E (0.95) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| Salicylamide SCHEMBL7198790 | 0.75 | KDM4E (0.95) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| Salicylamide SCHEMBL723112 | 0.75 | KDM4E (0.95) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| Salicylamide SCHEMBL6245272 | 0.75 | KDM4E (0.95) | KDM4EMAPTALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085194-A | Preparation method of 2- (2-hydroxyphenyl) -4H- [1,3] -benzoxazine-4-one | 青岛科技大学 | 2022-02-25 | — | — | CN | disclosed |