Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.40 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28707071 | 0.86 | CYP17A1 (0.43) | RXFP1HSP90AA1HSP90AB1LMNAPOLB | |
| SCHEMBL28856066 | 0.84 | RXFP1 (0.47) | RXFP1LMNAPOLBMETAP1KCNQ4 | |
| SCHEMBL2940952 | 0.83 | GAA (0.51) | RXFP1HSP90AA1HSP90AB1LMNAPOLB | |
| SCHEMBL29991642 | 0.83 | RXFP1 (0.46) | RXFP1HSP90AA1HSP90AB1LMNAPOLB | |
| SCHEMBL575004 | 0.83 | RXFP1 (0.46) | RXFP1HSP90AA1HSP90AB1LMNAPOLB | |
| SCHEMBL29909461 | 0.83 | RXFP1 (0.46) | RXFP1HSP90AA1HSP90AB1LMNAPOLB | |
| SCHEMBL29286688 | 0.83 | RXFP1 (0.46) | RXFP1HSP90AA1HSP90AB1LMNAPOLB | |
| SCHEMBL12517737 | 0.83 | RXFP1 (0.46) | RXFP1HSP90AA1HSP90AB1LMNAPOLB | |
| SCHEMBL29448807 | 0.83 | RXFP1 (0.46) | RXFP1HSP90AA1HSP90AB1LMNAPOLB | |
| SCHEMBL27913236 | 0.83 | RXFP1 (0.46) | RXFP1HSP90AA1HSP90AB1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |