Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14097857 | 0.91 | FFAR3 (0.52) | FFAR3MAPK1LMNANPSR1CYP2C19 | |
| SCHEMBL970790 | 0.86 | FFAR3 (0.56) | FFAR3MAPK1LMNANPSR1CYP2C19 | |
| SCHEMBL8052103 | 0.83 | FFAR3 (0.43) | FFAR3LMNAALDH1A1SLC1A2 | |
| SCHEMBL9042869 | 0.80 | FFAR3 (0.62) | FFAR3MAPK1LMNANPSR1CYP2C19 | |
| SCHEMBL1468704 | 0.80 | FFAR3 (0.62) | FFAR3MAPK1LMNANPSR1CYP2C19 | |
| SCHEMBL23458958 | 0.80 | FFAR3 (0.62) | FFAR3MAPK1LMNANPSR1CYP2C19 | |
| SCHEMBL9042716 | 0.80 | FFAR3 (0.62) | FFAR3MAPK1LMNANPSR1CYP2C19 | |
| SCHEMBL10203449 | 0.80 | FFAR3 (0.62) | FFAR3MAPK1LMNANPSR1CYP2C19 | |
| SCHEMBL5949421 | 0.80 | FFAR3 (0.62) | FFAR3MAPK1LMNANPSR1CYP2C19 | |
| SCHEMBL20255525 | 0.80 | FFAR3 (0.62) | FFAR3MAPK1LMNANPSR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174263-A | Non-lysosomal glucosylceramidase inhibitors and uses thereof | 阿勒克图治疗公司 | 2022-03-11 | — | — | CN | disclosed |