Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 20/20 | 1.00 |
| ▸ | SKP1 | P63208 | 20/20 | 1.00 |
| ▸ | SKP2 | Q13309 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28933440 | 0.87 | CKS1B (1.00) | CKS1BSKP1SKP2 | |
| SCHEMBL28707164 | 0.86 | CKS1B (1.00) | CKS1BSKP1SKP2 | |
| SCHEMBL30725782 | 0.86 | CKS1B (1.00) | CKS1BSKP1SKP2 | |
| SCHEMBL28933473 | 0.84 | CKS1B (1.00) | CKS1BSKP1SKP2 | |
| SCHEMBL30725767 | 0.84 | CKS1B (1.00) | CKS1BSKP1SKP2 | |
| SCHEMBL29161337 | 0.83 | CKS1B (0.72) | CKS1BSKP1SKP2 | |
| SCHEMBL30725774 | 0.83 | CKS1B (0.72) | CKS1BSKP1SKP2 | |
| SCHEMBL30929909 | 0.82 | CKS1B (0.74) | CKS1BSKP1SKP2 | |
| SCHEMBL28691788 | 0.81 | CKS1B (0.96) | CKS1BSKP1SKP2 | |
| SCHEMBL29161326 | 0.81 | CKS1B (1.00) | CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206499-A | 2,3, 5-Trisubstituted pyrazine compound and preparation method and application thereof | 郑州大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-118146165-A | 2,3, 5-Trisubstituted pyrazine compound and preparation method and application thereof | 郑州大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-113968824-B | 2,3, 5-trisubstituted pyrazine compound and preparation method and application thereof | 郑州大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-113968824-A | 2,3, 5-trisubstituted pyrazine compound and preparation method and application thereof | 郑州大学 | 2022-01-25 | — | — | CN | disclosed |