Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2997456 | 0.87 | CYP1A2 (0.53) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL30047158 | 0.85 | TSHR (0.54) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL2986904 | 0.85 | TSHR (0.54) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4428122 | 0.85 | MEN1 (0.54) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4426596 | 0.84 | KMT2A (0.51) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4432418 | 0.84 | CYP1A2 (0.56) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL1938386 | 0.83 | HPGD (0.55) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL2989262 | 0.83 | KMT2A (0.52) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5819265 | 0.82 | MEN1 (0.49) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5489641 | 0.81 | TSHR (0.56) | KMT2AMEN1CYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114085214-A | Sofantinib impurity and preparation method and application thereof | 和记黄埔医药（上海）有限公司 | 2022-02-25 | — | — | CN | disclosed |