Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | MELK | Q14680 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28681429 | 0.83 | CACNA1H (0.47) | CACNA1HNPSR1KDM4EALDH1A1MAPK1 | |
| SCHEMBL29491599 | 0.81 | NPSR1 (0.47) | NPSR1HTR2BIDO1APEX1TOP2A | |
| SCHEMBL11887806 | 0.79 | APEX1 (0.64) | NPSR1APEX1TOP2AKDM4ERECQL | |
| Cadaverine Tartrate SCHEMBL7964690 | 0.79 | CACNA1H (0.50) | CACNA1HHTR2BIDO1CACNA1GGRIN2B | |
| SCHEMBL4785390 | 0.78 | NPSR1 (0.75) | NPSR1APEX1TOP2AKDM4ERECQL | |
| SCHEMBL2996556 | 0.76 | NPSR1 (0.56) | NPSR1APEX1TOP2AKDM4ERECQL | |
| SCHEMBL29424865 | 0.76 | NPSR1 (0.56) | NPSR1APEX1TOP2AKDM4ERECQL | |
| SCHEMBL6092621 | 0.76 | KDM4E (0.68) | NPSR1APEX1TOP2AKDM4ERECQL | |
| Hydrochloric Acid SCHEMBL28877037 | 0.75 | KDM4E (0.66) | NPSR1APEX1TOP2AKDM4ERECQL | |
| SCHEMBL31695078 | 0.75 | APEX1 (0.59) | NPSR1APEX1TOP2AKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-A | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2021-08-06 | — | — | CN | disclosed |