Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22068975 | 0.88 | MAPT (0.37) | L3MBTL1MTORMAPTC5AR1ESR2 | |
| SCHEMBL22068991 | 0.86 | GCK (0.37) | L3MBTL1MTORMAPTC5AR1ADORA1 | |
| SCHEMBL22715571 | 0.83 | ADORA1 (0.46) | MTORMAPTC5AR1ESR2ADORA1 | |
| SCHEMBL22069029 | 0.82 | MAPT (0.34) | L3MBTL1MTORMAPTC5AR1ESR2 | |
| SCHEMBL22069268 | 0.82 | ADORA1 (0.38) | L3MBTL1MTORMAPTC5AR1ADORA1 | |
| SCHEMBL22029691 | 0.81 | ADORA1 (0.51) | MTORMAPTC5AR1ESR2ADORA1 | |
| SCHEMBL22727594 | 0.80 | MAPT (0.40) | MTORMAPTC5AR1ESR2ADORA1 | |
| SCHEMBL22716252 | 0.80 | ADORA1 (0.43) | MTORMAPTC5AR1ESR2ADORA1 | |
| SCHEMBL22102760 | 0.80 | PARP1 (0.40) | MTORMAPTC5AR1ESR2ADORA1 | |
| SCHEMBL22738284 | 0.80 | MAPT (0.41) | MTORMAPTC5AR1ESR2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843892-B | Oxadiazepinone derivatives and their use in the treatment of hepatitis B infections | 诺维拉治疗公司 | 2022-01-25 | — | — | CN | disclosed |