Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 20/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28701679 | 0.94 | GRIN1 (0.68) | GRIN1GRIN2B | |
| SCHEMBL22774882 | 0.89 | GRIN1 (0.67) | GRIN1GRIN2B | |
| SCHEMBL28936958 | 0.88 | GRIN1 (0.70) | GRIN1GRIN2B | |
| SCHEMBL22774681 | 0.87 | GRIN1 (0.65) | GRIN1GRIN2B | |
| SCHEMBL22771318 | 0.86 | GRIN1 (0.67) | GRIN1GRIN2B | |
| SCHEMBL22791956 | 0.86 | GRIN1 (0.69) | GRIN1GRIN2B | |
| SCHEMBL22771354 | 0.85 | GRIN1 (0.66) | GRIN1GRIN2B | |
| SCHEMBL22771440 | 0.85 | GRIN1 (0.66) | GRIN1GRIN2B | |
| SCHEMBL22771327 | 0.85 | GRIN1 (0.65) | GRIN1GRIN2B | |
| SCHEMBL22771324 | 0.85 | GRIN1 (0.65) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993583-A | Substituted pyrazolo [4,3-b ] pyridines and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2022-01-28 | — | — | CN | disclosed |