Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 16/20 | 0.77 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.71 |
| ▸ | PHGDH | O43175 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24861727 | 1.00 | PTGER4 (0.77) | PTGER4PTGER2PHGDH | |
| SCHEMBL24861981 | 0.93 | PTGER4 (0.70) | PTGER4PTGER2PHGDH | |
| SCHEMBL24861776 | 0.93 | PTGER4 (0.70) | PTGER4PTGER2PHGDH | |
| SCHEMBL26416996 | 0.92 | PTGER4 (0.65) | PTGER4PTGER2PHGDH | |
| SCHEMBL24861971 | 0.92 | PTGER4 (0.65) | PTGER4PTGER2PHGDH | |
| SCHEMBL28933699 | 0.89 | PTGER4 (0.62) | PTGER4PTGER2PHGDH | |
| SCHEMBL28699310 | 0.88 | PTGER4 (0.75) | PTGER4PTGER2PHGDH | |
| SCHEMBL28699311 | 0.88 | PTGER4 (0.75) | PTGER4PTGER2PHGDH | |
| SCHEMBL881243 | 0.87 | PTGER4 (1.00) | PTGER4PTGER2PHGDH | |
| SCHEMBL24861871 | 0.87 | PTGER4 (0.74) | PTGER4PTGER2PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354585-A | Synthesis of novel EP4 antagonists and their use in cancer and inflammation | 湖北生物医药产业技术研究院有限公司 | 2021-09-07 | — | — | CN | disclosed |