Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3961 | 0.98 | TDP1 (0.67) | TDP1TSHRLMNAALDH1A1CHRM2 | |
| SCHEMBL29521789 | 0.98 | TDP1 (0.67) | TDP1TSHRLMNAALDH1A1CHRM2 | |
| Hydrogen Sulfide SCHEMBL9879738 | 0.97 | TDP1 (0.65) | TDP1TSHRLMNAALDH1A1CHRM2 | |
| Hydrogen Sulfide SCHEMBL9879814 | 0.97 | TDP1 (0.65) | TDP1TSHRLMNAALDH1A1CHRM2 | |
| Hydrochloric Acid SCHEMBL11337068 | 0.97 | TDP1 (0.65) | TDP1TSHRLMNAALDH1A1CHRM2 | |
| Hydrogen Sulfide SCHEMBL9879813 | 0.97 | TDP1 (0.65) | TDP1TSHRLMNAALDH1A1CHRM2 | |
| SCHEMBL9879423 | 0.97 | TDP1 (0.65) | TDP1TSHRLMNAALDH1A1CHRM2 | |
| SCHEMBL3469 | 0.97 | TDP1 (0.65) | TDP1TSHRLMNAALDH1A1CHRM2 | |
| SCHEMBL9879199 | 0.97 | TDP1 (0.65) | TDP1TSHRLMNAALDH1A1CHRM2 | |
| SCHEMBL9878602 | 0.97 | TDP1 (0.65) | TDP1TSHRLMNAALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7736845-B2 | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue | CHEUNG DAVID T | 2010-06-15 | — | — | US | claimed |
| US-7687230-B2 | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue | CHEUNG DAVID T | 2010-03-30 | — | — | US | claimed |
| US-20100041010-A9 | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue | CHEUNG DAVID T | 2010-02-18 | — | — | US | claimed |
| US-20060127495-A1 | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue | CHEUNG DAVID T | 2006-06-15 | — | — | US | claimed |
| US-20060127876-A1 | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue | CHEUNG DAVID T | 2006-06-15 | — | — | US | claimed |
| US-7008763-B2 | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue | CHEUNG DAVID T | 2006-03-07 | — | — | US | claimed |
| US-20040057936-A1 | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue | CHEUNG DAVID T (US) | 2004-03-25 | — | — | US | claimed |
| CN-122079986-A | Salts of compounds and crystalline forms thereof | — | 2026-05-26 | — | — | CN | disclosed |
| EP-4023225-B1 | COMBINATIONS OF A SALICYLATE AND TRIMETAZIDINE FOR USE IN THE TREATMENT OF METABOLIC DISEASES | INST ZOOLOGY CAS (CN) | 2026-01-28 | — | — | EP | disclosed |
| CN-114369093-B | Salts of compounds and crystalline forms thereof | 和记黄埔医药（上海）有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-114044776-B | Salts of compounds and crystalline forms thereof | 和记黄埔医药（上海）有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-118765282-A | Anti-NGF antibodies and uses thereof | 因外泰克斯股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-111039939-B | Heteroaryl amides as inhibitors of protein aggregation | 优时比生物医药有限公司 | 2023-09-19 | — | — | CN | disclosed |
| US-20060193885-A1 | Implantable biomaterial and a method of producing same | CELXCEL PTY LTD (AU) | 2006-08-31 | — | — | US | disclosed |
| WO-2006066327-A1 | AN IMPLANTABLE BIOMATERIAL AND A METHOD OF PRODUCING SAME | CELXCEL PTY LTD (AU) | 2006-06-29 | — | — | WO | disclosed |
| US-20060127495-A1 | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue | CHEUNG DAVID T | 2006-06-15 | — | — | US | disclosed |
| US-20060127876-A1 | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue | CHEUNG DAVID T | 2006-06-15 | — | — | US | disclosed |
| US-7008763-B2 | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue | CHEUNG DAVID T | 2006-03-07 | — | — | US | disclosed |
| US-20040057936-A1 | Method to treat collagenous connective tissue for implant remodeled by host cells into living tissue | CHEUNG DAVID T (US) | 2004-03-25 | — | — | US | disclosed |
| US-4067974-A | Stabilized solid form choline salicylate compositions | THE PURDUE FREDERICK COMPANY (US) | 1978-01-10 | — | — | US | disclosed |