Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.86 |
| ▸ | BCHE | P06276 | 4/20 | 0.74 |
| ▸ | ACHE | P22303 | 4/20 | 0.74 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29416643 | 1.00 | MAOB (0.86) | MAOBBCHEACHEMAOAMEN1 | |
| SCHEMBL29416639 | 0.95 | MAOB (0.86) | MAOBBCHEACHEMAOA | |
| SCHEMBL29416648 | 0.94 | MAOB (0.86) | MAOBBCHEACHEMAOA | |
| SCHEMBL28701635 | 0.93 | MAOB (0.73) | MAOBBCHEACHE | |
| SCHEMBL29416618 | 0.93 | MAOB (0.73) | MAOBBCHEACHE | |
| SCHEMBL28695564 | 0.91 | MAOB (0.71) | MAOBBCHEACHEMAOAMEN1 | |
| SCHEMBL29416705 | 0.91 | MAOB (0.71) | MAOBBCHEACHEMAOAMEN1 | |
| SCHEMBL29416672 | 0.87 | MAOB (0.74) | MAOBBCHEACHE | |
| SCHEMBL29416737 | 0.86 | MAOB (0.74) | MAOBBCHEACHE | |
| SCHEMBL28684813 | 0.86 | MAOB (0.71) | MAOBBCHEACHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105753-B | Fisetin derivative and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2024-02-20 | — | — | CN | claimed |
| CN-114105753-A | Fisetin derivative and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2022-03-01 | — | — | CN | claimed |
| CN-114105753-B | Fisetin derivative and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2024-02-20 | — | — | CN | disclosed |
| CN-114105753-A | Fisetin derivative and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2022-03-01 | — | — | CN | disclosed |