SCHEMBL28705111

SCHEMBL28705111

C=C(O)Cc1ccc(C(=O)c2ccccc2)c(O)c1OCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.47
KDM4E B2RXH2 5/20 0.47
ALOX15 P16050 4/20 0.47
HSD17B10 Q99714 4/20 0.47
MAPK1 P28482 3/20 0.47
CCNB2 O95067 2/20 0.46
CCNE2 O96020 2/20 0.46
CDK1 P06493 2/20 0.46
CCNB1 P14635 2/20 0.46
CCNE1 P24864 2/20 0.46
CDK2 P24941 2/20 0.46
CCNB3 Q8WWL7 2/20 0.46
HPGD P15428 5/20 0.41
ALDH1A1 P00352 3/20 0.41
RECQL P46063 3/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
ALOX12 P18054 1/20 0.41
LMNA P02545 5/20 0.40
HTT P42858 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28495783 0.83 CCNB2 (0.51) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL10758904 0.81 MAPT (0.48) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL2031168 0.79 CCNB2 (0.49) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL28705108 0.77 CCNB2 (0.46) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL11499163 0.76 MAPT (0.46) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL10980663 0.76 CCNE2 (0.47) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL5413933 0.76 MAPT (0.60) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL28488245 0.74 CCNB2 (0.52) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL5478807 0.74 CCNB2 (0.50) MAPTKDM4EALOX15HSD17B10MAPK1
SCHEMBL5829566 0.73 MAPT (0.51) MAPTKDM4EALOX15HSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114058142-A Transparent fluorine-containing polymer film 浙江省化工研究院有限公司 2022-02-18 CN claimed
CN-114058142-B Transparent fluorine-containing polymer film 浙江省化工研究院有限公司 2023-05-12 CN disclosed
CN-114058142-A Transparent fluorine-containing polymer film 浙江省化工研究院有限公司 2022-02-18 CN disclosed