Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | TP53 | P04637 | 7/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28705989 | 0.99 | MAPT (0.82) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28683361 | 0.96 | MAPT (0.84) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28705189 | 0.94 | MAPT (0.70) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28932886 | 0.93 | MAPT (0.72) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28703794 | 0.92 | MAPT (0.88) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28696154 | 0.90 | MAPT (0.73) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28932883 | 0.90 | MAPT (1.00) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28690108 | 0.88 | MAPT (0.79) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28703720 | 0.87 | MAPT (0.93) | MAPTTP53ALDH1A1LMNAGAA | |
| SCHEMBL28703726 | 0.87 | MAPT (0.93) | MAPTTP53ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057626-A | Indole-2, 3-dione derivative, preparation method thereof and anti-liver cancer drug for inhibiting RECQL4 specific expression | 山东第一医科大学(山东省医学科学院) | 2022-02-18 | — | — | CN | disclosed |