Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.47 |
| ▸ | MTOR | P42345 | 4/20 | 0.47 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 7/20 | 0.42 |
| ▸ | NRAS | P01111 | 1/20 | 0.42 |
| ▸ | EIF2AK4 | Q9P2K8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29544366 | 1.00 | PIK3CA (0.47) | PIK3CAMTORMAP3K14FLT3NRAS | |
| SCHEMBL3310129 | 0.86 | FLT3 (0.43) | PIK3CAMTORFLT3NRASEIF2AK4 | |
| SCHEMBL22228874 | 0.86 | MAP3K14 (0.49) | PIK3CAMTORMAP3K14FLT3NRAS | |
| SCHEMBL22228697 | 0.84 | FLT3 (0.44) | PIK3CAMTORFLT3NRASEIF2AK4 | |
| SCHEMBL20455512 | 0.84 | MAP3K14 (0.47) | PIK3CAMTORMAP3K14FLT3NRAS | |
| SCHEMBL20455687 | 0.82 | EIF2AK4 (0.52) | FLT3NRASEIF2AK4 | |
| SCHEMBL20455535 | 0.81 | FLT3 (0.44) | PIK3CAMTORFLT3NRASMAPT | |
| SCHEMBL700990 | 0.78 | FLT3 (0.52) | PIK3CAMTORFLT3MAPT | |
| SCHEMBL20455515 | 0.78 | FLT3 (0.40) | FLT3NRASEIF2AK4GAAMAPT | |
| SCHEMBL3315522 | 0.75 | IGF1R (0.44) | PIK3CAMTORMAP3K14FLT3NRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269742-A | Derivatives of 4- (imidazo [1,2-a ] pyridin-3-yl) -N- (pyridinyl) pyrimidin-2-amines as therapeutic agents | 常州千红生化制药股份有限公司 | 2022-04-01 | — | — | CN | disclosed |