Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.37 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28705000 | 0.85 | NQO2 (0.39) | MIFRXFP1NQO2POLBCYP17A1 | |
| SCHEMBL29618957 | 0.83 | HPGD (0.47) | MIFRXFP1NQO2POLBCYP17A1 | |
| SCHEMBL24362149 | 0.83 | HPGD (0.47) | MIFRXFP1NQO2POLBCYP17A1 | |
| SCHEMBL19519029 | 0.81 | KMT2A (0.53) | RXFP1POLBALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2770751 | 0.80 | SMN1; SMN2 (0.47) | MIFRXFP1NQO2POLBALDH1A1 | |
| SCHEMBL29958958 | 0.80 | SMN1; SMN2 (0.47) | MIFRXFP1NQO2POLBALDH1A1 | |
| SCHEMBL2363945 | 0.79 | CYP17A1 (0.53) | MIFRXFP1NQO2POLBCYP17A1 | |
| SCHEMBL31619048 | 0.79 | KMT2A (0.52) | MIFRXFP1ALDH1A1MAPTLMNA | |
| SCHEMBL1767849 | 0.79 | KMT2A (0.52) | MIFRXFP1ALDH1A1MAPTLMNA | |
| SCHEMBL29834708 | 0.79 | CYP17A1 (0.53) | MIFRXFP1NQO2POLBCYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999057-A1 | POLYAROMATIC UREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF MUSCLE DISEASES | ANAGENESIS BIOTECHNOLOGIES SAS (FR) | 2022-05-25 | — | — | EP | disclosed |
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |