Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.62 |
| ▸ | PARP15 | Q460N3 | 6/20 | 0.62 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.62 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10328684 | 0.86 | PARP10 (0.53) | PARP10PARP15PARP2CYP4F2CYP4A11 | |
| SCHEMBL457981 | 0.86 | P4HTM (0.56) | PARP10PARP15PARP2CYP4F2CYP4A11 | |
| SCHEMBL22583269 | 0.84 | PARP10 (0.50) | PARP10PARP15PARP2CYP4F2CYP4A11 | |
| SCHEMBL31681177 | 0.83 | PARP15 (0.49) | PARP10PARP15PARP2CYP4F2CYP4A11 | |
| SCHEMBL1173221 | 0.82 | MAPK1 (0.51) | PARP10PARP15PARP2CYP4F2CYP4A11 | |
| Nitrous Acid SCHEMBL28713860 | 0.81 | PARP10 (0.48) | PARP10PARP15PARP2LRRK2CYP4F2 | |
| SCHEMBL28698673 | 0.78 | PDE4A (0.50) | PARP10CYP4F2CYP4A11OPRM1OPRD1 | |
| SCHEMBL20812681 | 0.77 | CNR2 (0.60) | MCHR1 | |
| SCHEMBL6302880 | 0.77 | PARP10 (0.58) | PARP10OPRM1OPRD1OPRK1KMT2A | |
| SCHEMBL19309297 | 0.77 | KMT2A (0.50) | PARP10CYP4F2CYP4A11BACE1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072395-A | Heterocyclic compounds and their use for treating helminth infections and diseases | 新基公司 | 2022-02-18 | — | — | CN | disclosed |