Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.55 |
| ▸ | AXL | P30530 | 2/20 | 0.55 |
| ▸ | SRC | P12931 | 3/20 | 0.52 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.45 |
| ▸ | MET | P08581 | 2/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | ACOX3 | O15254 | 1/20 | 0.45 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.45 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.45 |
| ▸ | STK10 | O94804 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1521770 | 0.80 | ABL1 (0.53) | ABL1AXLSRCEPHB4MAPK14 | |
| SCHEMBL2028017 | 0.80 | GRN (0.62) | ABL1AXLSRCEPHB4MAPK14 | |
| SCHEMBL17436825 | 0.79 | CDK8 (0.60) | MAPK14PTK2MAPK11DDR2MAPK13 | |
| SCHEMBL3379365 | 0.79 | GRN (0.59) | MAPK14MAPK11JAK2NTRK1MAPK13 | |
| SCHEMBL28684775 | 0.78 | MAPK14 (0.51) | MAPK14PTK2MAPK11DDR2MAPK13 | |
| SCHEMBL2024393 | 0.77 | ABL1 (0.53) | ABL1AXLSRCEPHB4MAPK14 | |
| SCHEMBL30904919 | 0.77 | ABL1 (0.52) | ABL1AXLSRCEPHB4MAPK14 | |
| SCHEMBL29186401 | 0.77 | ABL1 (0.52) | ABL1AXLSRCEPHB4MAPK14 | |
| SCHEMBL29396477 | 0.76 | ABL1 (0.67) | ABL1AXLSRCEPHB4MAPK14 | |
| SCHEMBL28700821 | 0.76 | ABL1 (0.67) | ABL1AXLSRCEPHB4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144410-A | Polyarylurea derivatives and their use in the treatment of muscular diseases | 阿纳格纳斯生物技术股份有限公司 | 2022-03-04 | — | — | CN | disclosed |