Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29406911 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL30073372 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL1758897 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL18585192 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL454108 | 0.84 | KDM4E (0.53) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL11425376 | 0.82 | CA12 (0.52) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL15407272 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL31325048 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL20844678 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL16396676 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1MAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105790-A | Preparation method of 3-amino-4, 5-dibromobenzoic acid methyl ester | 无锡捷化医药科技有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-114105790-A | Preparation method of 3-amino-4, 5-dibromobenzoic acid methyl ester | 无锡捷化医药科技有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114105790-A | Preparation method of 3-amino-4, 5-dibromobenzoic acid methyl ester | 无锡捷化医药科技有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114105790-A | Preparation method of 3-amino-4, 5-dibromobenzoic acid methyl ester | 无锡捷化医药科技有限公司 | 2022-03-01 | — | — | CN | disclosed |