Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.61 |
| ▸ | BCR | P11274 | 9/20 | 0.61 |
| ▸ | PDGFRA | P16234 | 12/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.60 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.60 |
| ▸ | KIT | P10721 | 5/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | PRKCA | P17252 | 1/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.57 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29551443 | 1.00 | ABL1 (0.61) | ABL1BCRPDGFRAPDGFRBDDR1 | |
| SCHEMBL24250918 | 0.92 | ABL1 (0.62) | ABL1BCRPDGFRAPDGFRBDDR1 | |
| SCHEMBL29551241 | 0.92 | ABL1 (0.62) | ABL1BCRPDGFRAPDGFRBDDR1 | |
| SCHEMBL24250999 | 0.92 | PDGFRA (0.65) | ABL1BCRPDGFRAPDGFRBDDR1 | |
| SCHEMBL29551463 | 0.91 | ABL1 (0.57) | ABL1BCRPDGFRAPDGFRBDDR1 | |
| SCHEMBL24251083 | 0.91 | ABL1 (0.57) | ABL1BCRPDGFRAPDGFRBDDR1 | |
| SCHEMBL24251016 | 0.90 | PDGFRA (0.71) | ABL1BCRPDGFRAPDGFRBDDR1 | |
| SCHEMBL29551537 | 0.90 | PDGFRA (0.71) | ABL1BCRPDGFRAPDGFRBDDR1 | |
| SCHEMBL24251078 | 0.89 | ABL1 (0.48) | ABL1BCRPDGFRAPDGFRBDDR1 | |
| SCHEMBL24251081 | 0.87 | PDGFRA (0.58) | ABL1BCRPDGFRAPDGFRBDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127065-A | Compounds for the treatment of neurodegenerative diseases and cancer | 鸿仪有限责任公司 | 2022-03-01 | — | — | CN | claimed |