Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5288663 | 0.92 | HRH2 (0.61) | HRH2HRH3 | |
| SCHEMBL10527698 | 0.92 | HRH2 (0.61) | HRH2HRH3 | |
| SCHEMBL10689006 | 0.92 | HRH2 (0.61) | HRH2HRH3 | |
| SCHEMBL30597717 | 0.92 | HRH2 (0.61) | HRH2HRH3 | |
| SCHEMBL10679839 | 0.92 | HRH2 (0.61) | HRH2HRH3 | |
| SCHEMBL9551700 | 0.91 | HRH2 (0.59) | HRH2KDM4EALDH1A1HRH3 | |
| SCHEMBL9574750 | 0.89 | HRH2 (0.61) | HRH2HRH3 | |
| SCHEMBL9551695 | 0.88 | HRH2 (0.56) | HRH2KDM4EHRH3 | |
| SCHEMBL10401176 | 0.87 | HRH2 (0.62) | HRH2HRH3 | |
| SCHEMBL10982783 | 0.87 | HRH2 (0.62) | HRH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195739-A | High-purity roxatidine acetate hydrochloride, intermediate thereof and preparation methods thereof | 广安凯特制药有限公司 | 2022-03-18 | — | — | CN | claimed |
| CN-114195739-A | High-purity roxatidine acetate hydrochloride, intermediate thereof and preparation methods thereof | 广安凯特制药有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114195739-A | High-purity roxatidine acetate hydrochloride, intermediate thereof and preparation methods thereof | 广安凯特制药有限公司 | 2022-03-18 | — | — | CN | disclosed |